Shilpa Kadam, Ph.D.

Shilpa Kadam
Shilpa Kadam
Research Scientist and Director of the Mouse In-Vivo Electrophysiology Laboratory, Kennedy Krieger Institute

Kennedy Krieger Institute
716 N. Broadway
Baltimore, MD 21205
Phone: (443) 923-2688
Email: Kadam@kennedykrieger.org

Dr. Shilpa Kadam is a research scientist at the Hugo W. Moser Research Institute at Kennedy Krieger. She is an assistant professor of neurology at the Kennedy Krieger Institute and Johns Hopkins University School of Medicine. She is also the director of the mouse in-vivo electrophysiology laboratory at the Kennedy Krieger Institute.


Biographical Sketch:

Shilpa Kadam graduated with her diploma in alternative medicine and completed her internship at Sanjeevan General Hospital in Pune, India. After graduation, she trained/worked as a medical officer at the Pune Institute of Neurology in the intensive care and high dependency units. She completed her doctoral degree in the United States in the field epilepsy research in the lab of Dr. F. E. Dudek (University of Utah School of Medicine), in 2006. She did her post-doctoral fellowship training in the Department of Neurology at the Johns Hopkins University School of Medicine. In 2008, she joined the faculty of the Neurology Department.


Research Summary:

Dr. Kadam's doctoral research involved the study of epileptogenesis using in vivo ECOG monitoring using telemetry and in vitro slice electrophysiology in a rat model of perinatal hypoxia-ischemia. During her fellowship training at Hopkins, she helped complete projects investigating the effect of neonatal stroke in a new mouse model established by the Comi laboratory on endogenous neurogenesis in the neurogenic niches of the sub-granular and sub-ventricular zones in the central nervous system. Using the expertise gained during her pre-doctoral training in the Dudek Lab, she has established a mouse electroencephalogram (EEG) laboratory at the Kennedy Krieger Institute with capabilities of recording chronic and continuous EEGs. Dr. Kadam is interested in investigating epileptogenesis in animal models of developmental disabilities with the goal to test novel therapies. Her current research projects involve characterizing the acute electrographic seizures and investigating the evolution of refractoriness following ischemia in the neonatal period. She is also leading a study investigating the role of MeCP2 in epileptogenesis and activity dependent glutamate homeostasis in-vivo.