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Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese.
|Title||Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Zhang X, Zhang C, Wu Z, Wang Z, Peng D, Chen J, Hong W, Yuan C, Li Z, Yu S, Fang Y|
|Journal||Journal of affective disorders|
|Date Published||2013 Sep 5|
A growing body of evidence highlights the existence of shared genetic susceptibility to both major depressive disorder (MDD) and bipolar disorder (BD), suggesting some potential genetic overlap between the disorders. Genome-wide association studies have identified consistent association of single nucleotide polymorphisms of the α-1 C subunit of the L-type voltage-gated calcium channel gene (CACNA1C) with MDD and BD, suggesting CACNA1C as a promising candidate gene for susceptibility to mood disorders. In the present study, we tested the association of CACNA1C with MDD and BD in Han Chinese.
|Alternate Journal||J Affect Disord|