Can stroma reaction predict cancer lethality?

TitleCan stroma reaction predict cancer lethality?
Publication TypeJournal Article
Year of Publication2013
AuthorsFreeman MR, Li Q, Chung LWK
JournalClinical cancer research : an official journal of the American Association for Cancer Research
Volume19
Issue18
Pagination4905-7
Date Published2013 Sep 15
Abstract

Stromal features in carcinomas may provide a relatively consistent means to stratify patients afflicted with solid tumors. Stroma-derived transcriptome signatures can now be used to make predictions about patient survival, suggesting the potential for their clinical application in precision medicine to predict disease progression and emergence of therapeutic resistance.

DOI10.1371/journal.pone.0073023
Alternate JournalClin. Cancer Res.