News & Updates
Search Research Content
Resource Finder at Kennedy Krieger Institute
A free resource that provides access to information and support for individuals and families living with developmental disabilities.
Daphmacromines K-O, alkaloids from Daphniphyllum macropodum.
|Title||Daphmacromines K-O, alkaloids from Daphniphyllum macropodum.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Cao M-M, Wang L, Zhang Y, He H-P, Gu Y-C, Zhang Q, Li Y, Yuan C-M, Li S-L, Di Y-T, Hao X-J|
|Date Published||2013 Sep|
Five new yuzurimine-type Daphniphyllum alkaloids, daphmacromines K-O (1-5), were isolated from the leaves and stems of Daphniphyllum macropodum. Their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. Daphmacromine O (5) showed moderate cytotoxic activity against brine shrimp.