Diffusion imaging of human breast.

TitleDiffusion imaging of human breast.
Publication TypeJournal Article
Year of Publication1997
AuthorsEnglander SA, Uluğ AM, Brem R, Glickson JD, van Zijl PC
JournalNMR in biomedicine
Volume10
Issue7
Pagination348-52
Date Published1997 Oct
Abstract

It is shown that diffusion-weighted imaging is possible in the human breast. Diffusion constants were measured in the breast parenchyma of four volunteers with no known breast lesions. The apparent diffusion constant of water measured in regions of interest chosen in normal human breast fibroglandular tissue was 1.64 +/- 0.19 x 10(-5) cm2/S and that measured in the area of fatty breast tissue was 0.32 +/- 0.18 x 10(-5) cm2/S. The resulting images indicate that fibroglandular tissue and fat can be clearly distinguished in diffusion-weighted as well as in absolute diffusion images of the breast. Potential future applications of this technology for the study of breast pathologies are suggested.

DOI10.1371/journal.pone.0048500
Alternate JournalNMR Biomed