Essential Role of CD11a in CD8+ T-Cell Accumulation and Activation in Adipose Tissue.

TitleEssential Role of CD11a in CD8+ T-Cell Accumulation and Activation in Adipose Tissue.
Publication TypeJournal Article
Year of Publication2014
AuthorsJiang E, Perrard XD, Yang D, Khan IM, Perrard JL, Smith WC, Ballantyne CM, Wu H
JournalArteriosclerosis, thrombosis, and vascular biology
Volume34
Issue1
Pagination34-43
Date Published2014 Jan
Abstract

T cells, particularly CD8(+) T cells, are major participants in obesity-linked adipose tissue (AT) inflammation. We examined the mechanisms of CD8(+) T-cell accumulation and activation in AT and the role of CD11a, a β2 integrin.

DOI10.1152/ajplung.00423.2012
Alternate JournalArterioscler. Thromb. Vasc. Biol.