News & Updates
Search Research Content
Resource Finder at Kennedy Krieger Institute
A free resource that provides access to information and support for individuals and families living with developmental disabilities.
An extensive epidemiological investigation of a kidney cancer cluster in a chemical plant: what have we learned?
|Title||An extensive epidemiological investigation of a kidney cancer cluster in a chemical plant: what have we learned?|
|Publication Type||Journal Article|
|Year of Publication||2014|
|Authors||Iwatsubo Y, Bénézet L, Boutou-Kempf O, Févotte J, Garras L, Goldberg M, Luce D, Pilorget C, Imbernon E|
|Journal||Occupational and environmental medicine|
|Date Published||2014 Jan|
In 2003, a cluster of renal cell carcinoma (RCC) cases was reported among men working at a French chemical plant using a proprietary process to produce vitamin A. The 10 index cases yielded a standardised incidence ratio of 13.1 for 1994-2002. Nine of these 10 cases were diagnosed by a plant-specific abdominal ultrasonography screening programme that targeted exposure to an intermediate chemical, 4-chloro-1,1-dimethoxy-3-methyl-2-butene, commonly named 'chloracetal C5', suspected as the cause by some experts. Epidemiological investigations sought to examine the relations between occupational exposures and RCC.
|Alternate Journal||Occup Environ Med|