Fast skeletal muscle troponin activator in the dy2J muscular dystrophy model.

TitleFast skeletal muscle troponin activator in the dy2J muscular dystrophy model.
Publication TypeJournal Article
Year of Publication2013
AuthorsMiciak JJ, Warsing LC, Tibbs ME, Jasper JR, Jampel SB, Malik FI, Tankersley C, Wagner KR
JournalMuscle & nerve
Volume48
Issue2
Pagination279-85
Date Published2013 Aug
Abstract

Tirasemtiv is a novel small molecule activator of the fast skeletal muscle troponin complex that produces sensitization of the sarcomere to calcium. Tirasemtiv is currently in Phase II clinical trials for neuromuscular disease.

DOI10.1002/mus.23848
Alternate JournalMuscle Nerve