Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.

TitleGenetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.
Publication TypeJournal Article
Year of Publication2013
AuthorsGeisbrecht ER, Sawant K, Su Y, Liu ZC, Silver DL, Burtscher A, Wang X, Zhu AJ, McDonald JA
JournalDevelopmental dynamics : an official publication of the American Association of Anatomists
Volume242
Issue5
Pagination414-31
Date Published2013 May
Abstract

Cell motility is essential for embryonic development and physiological processes such as the immune response, but also contributes to pathological conditions such as tumor progression and inflammation. However, our understanding of the mechanisms underlying migratory processes is incomplete. Drosophila border cells provide a powerful genetic model to identify the roles of genes that contribute to cell migration.

DOI10.1167/iovs.12-10847
Alternate JournalDev. Dyn.