High-dose cyclophosphamide for graft-versus-host disease prevention.

TitleHigh-dose cyclophosphamide for graft-versus-host disease prevention.
Publication TypeJournal Article
Year of Publication2010
AuthorsLuznik L, Jones RJ, Fuchs EJ
JournalCurrent opinion in hematology
Volume17
Issue6
Pagination493-9
Date Published2010 Nov
Abstract

Administration of high-dose cyclophosphamide after transplantation inhibits both graft rejection and graft-versus-host disease (GvHD) in mouse models of allogeneic blood or marrow transplantation (alloBMT). This strategy has recently been adapted to human transplantation.

DOI10.1097/BRS.0b013e3181e7d675
Alternate JournalCurr. Opin. Hematol.