Hybrid assemblies based on a gadolinium-containing polyoxometalate and a cationic polymer with spermine side chains for enhanced MRI contrast agents.

TitleHybrid assemblies based on a gadolinium-containing polyoxometalate and a cationic polymer with spermine side chains for enhanced MRI contrast agents.
Publication TypeJournal Article
Year of Publication2013
AuthorsChai W, Wang S, Zhao H, Liu G, Fischer K, Li H, Wu L, Schmidt M
JournalChemistry (Weinheim an der Bergstrasse, Germany)
Volume19
Issue40
Pagination13317-21
Date Published2013 Sep 27
Abstract

Supramolecular assembly: Spherical and stable hybrid assemblies based on a cationic polymer with spermine side chains and an anionic Gd(3+)-containing polyoxometalate cluster (GdW) are prepared by electrostatic interaction. The T1-weighted MRI performance of GdW is enhanced about three times in the assemblies; meanwhile, the assemblies show good biocompatibility, which enables them to be promising candidates for MRI contrast agents.

DOI10.7717/peerj.132
Alternate JournalChemistry