Mimicking the binding and unbinding of Fe3+ with transferrin using a single biomimetic nanochannel.

TitleMimicking the binding and unbinding of Fe3+ with transferrin using a single biomimetic nanochannel.
Publication TypeJournal Article
Year of Publication2013
AuthorsZhao C, Li X, Li L, Gong X, Chang Y, Zheng J
JournalChemical communications (Cambridge, England)
Volume49
Issue81
Pagination9317-9
Date Published2013 Oct 18
Abstract

A new type of apo-Tf functionalized nanochannel is developed to achieve the specific and selective binding and unbinding of Fe(3+) in a multiple and reversible manner via a protein-conformation-gating mechanism. This ion-responsive biomimetic nanochannel provides a simple, robust, and promising model for studying other biological processes.

DOI10.1039/c3cc44249g
Alternate JournalChem. Commun. (Camb.)