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Neuroanatomic variation in monozygotic twin pairs discordant for the narrow phenotype for autism.
|Title||Neuroanatomic variation in monozygotic twin pairs discordant for the narrow phenotype for autism.|
|Publication Type||Journal Article|
|Year of Publication||2004|
|Authors||Kates WR, Burnette CP, Eliez S, Strunge LA, Kaplan D, Landa R, Reiss AL, Pearlson GD|
|Journal||The American journal of psychiatry|
|Date Published||2004 Mar|
The broader autism phenotype includes relatives of individuals with autism who display social and language deficits that are qualitatively similar to those of autism but less severe. In previous studies of monozygotic twins discordant for autism, more than 75% of the twins without autism displayed the broader phenotype. Differences in neuroanatomy between discordant monozygotic twins might be associated with the narrow and broader behavioral phenotypes. The authors examined the relationship of twin pair differences in clinical phenotype to differences in neuroanatomic phenotype.
|Alternate Journal||Am J Psychiatry|