Notch1-Nuclear Factor κB Involves in Oxidative Stress-Induced Alcoholic Steatohepatitis.

TitleNotch1-Nuclear Factor κB Involves in Oxidative Stress-Induced Alcoholic Steatohepatitis.
Publication TypeJournal Article
Year of Publication2014
AuthorsWang C, Li X, Wang H, Xie Q, Xu Y
JournalAlcohol and alcoholism (Oxford, Oxfordshire)
Volume49
Issue1
Pagination10-6
Date Published2014 Jan-Feb
Abstract

The Notch1 signaling pathway is implicated in multiple inflammatory diseases. However, the role of Notch1 signaling in alcoholic steatohepatitis (ASH) has not been fully investigated. We aimed to determine whether Notch1-Nuclear factor-κB (NF-κB) signaling mediates oxidative stress-induced ASH.

DOI10.1073/pnas.1318830110
Alternate JournalAlcohol Alcohol.