Photodynamic therapy for high-grade dysplasia of bile duct via a choledochoscope.

TitlePhotodynamic therapy for high-grade dysplasia of bile duct via a choledochoscope.
Publication TypeJournal Article
Year of Publication2013
AuthorsZhou J-J, Xiong L, Li Q-L, Gu Y, Wen Y, Deng X-F, Miao X-Y
JournalWorld journal of gastroenterology : WJG
Volume19
Issue33
Pagination5590-2
Date Published2013 Sep 7
Abstract

When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia, it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy. Here we describe a patient with a progressive dysplastic lesion in the common bile duct, which developed from moderate-high to high-grade dysplasia in approximately 2 mo. The patient refused major surgery. Therefore, endoscopic-assisted photodynamic therapy was performed. The result at follow-up using a trans-T-tube choledochoscope showed that the lesion was completely necrotic. This report is the first to describe the successful treatment of high-grade dysplasia of the distal bile duct using photodynamic therapy via a choledochoscope.

DOI10.4103/2249-4847.106008
Alternate JournalWorld J. Gastroenterol.