Pulmonary function in patients with amyotrophic lateral sclerosis at disease onset.

TitlePulmonary function in patients with amyotrophic lateral sclerosis at disease onset.
Publication TypeJournal Article
Year of Publication2012
AuthorsChandrasoma B, Balfe D, Naik T, Elsayegh A, Lewis M, Mosenifar Z
JournalMonaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo
Volume77
Issue3-4
Pagination129-33
Date Published2012 Sep-Dec
Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting both the upper and lower motor neurons. Deteriorating pulmonary function as a reflection of progressive respiratory muscle weakness is a common feature, accounting for the majority of deaths. The aim of the study was to describe a trend in initial pulmonary function tests (PFT) of amyotrophic lateral sclerosis (ALS) patients, in addition, differentiating between the types of disease onset, bulbar, limb muscle, and a combination.

DOI10.1155/2013/972347
Alternate JournalMonaldi Arch Chest Dis