Quantitative assessment of lung cancer associated with genes methylation in the peripheral blood.

TitleQuantitative assessment of lung cancer associated with genes methylation in the peripheral blood.
Publication TypeJournal Article
Year of Publication2013
AuthorsTan S, Sun C, Wei X, Li Y, Wu Y, Yan Z, Feng F, Wang J, Wu Y
JournalExperimental lung research
Volume39
Issue4-5
Pagination182-90
Date Published2013 May-Jun
Abstract

Lung cancer is the leading cause of cancer-related deaths worldwide due mainly to late diagnosis and poor prognosis. Aberrant promoter methylation is an important mechanism for silencing of tumor suppressor genes during carcinogenesis and a promising tool for the development of molecular biomarkers.

DOI10.1371/journal.pone.0066791
Alternate JournalExp. Lung Res.