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Representation of internal models of action in the autistic brain.
|Title||Representation of internal models of action in the autistic brain.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Haswell CC, Izawa J, Dowell LR, Mostofsky SH, Shadmehr R|
|Date Published||2009 Aug|
Children with autism spectrum disorder (ASD) have deficits in motor control, imitation and social function. Does a dysfunction in the neural basis of representing internal models of action contribute to these problems? We measured patterns of generalization as children learned to control a novel tool and found that the autistic brain built a stronger than normal association between self-generated motor commands and proprioceptive feedback; furthermore, the greater the reliance on proprioception, the greater the child's impairments in social function and imitation.
|Alternate Journal||Nat. Neurosci.|