Restoring function after spinal cord injury: promoting spontaneous regeneration with stem cells and activity-based therapies.

TitleRestoring function after spinal cord injury: promoting spontaneous regeneration with stem cells and activity-based therapies.
Publication TypeJournal Article
Year of Publication2007
AuthorsBelegu V, Oudega M, Gary DS, McDonald JW
JournalNeurosurgery clinics of North America
Volume18
Issue1
Pagination143-68, xi
Date Published2007 Jan
Abstract

Although neural regeneration is an active research field today, no current treatments can aid regeneration after spinal cord injury. This article reviews the feasibility of spinal cord repair and provides an overview of the range of strategies scientists are taking toward regeneration. The major focus of this article is the future role of stem cell transplantation and similar rehabilitative restorative approaches designed to optimize spontaneous regeneration by mobilizing endogenous stem cells and facilitating other cellular mechanisms of regeneration, such as axonal growth and myelination.

DOI10.1007/s11832-007-0006-8
Alternate JournalNeurosurg. Clin. N. Am.