Simultaneous determination of phenylalanine and tyrosine in peripheral capillary blood by HPLC with ultraviolet detection.

TitleSimultaneous determination of phenylalanine and tyrosine in peripheral capillary blood by HPLC with ultraviolet detection.
Publication TypeJournal Article
Year of Publication2013
AuthorsMo X-M, Li Y, Tang A-G, Ren Y-P
JournalClinical biochemistry
Volume46
Issue12
Pagination1074-8
Date Published2013 Aug
Abstract

Phenylalanine (Phe) and tyrosine (Tyr) are the most reliable indicators for the diagnosis of phenylketonuria (PKU). The purpose of this study is to establish a simple and rapid method for the determination of Phe and Tyr in peripheral capillary blood from newborns and children by high performance liquid chromatography with ultraviolet detection (HPLC-UV).

DOI10.1039/c3an00948c
Alternate JournalClin. Biochem.