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THERMODYNAMIC CHARACTERIZATION OF METAL PHTHALOCYANINES-HUMAN SERUM ALBUMIN INTERACTIONS.
|Title||THERMODYNAMIC CHARACTERIZATION OF METAL PHTHALOCYANINES-HUMAN SERUM ALBUMIN INTERACTIONS.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Jones CL, Jones C, Thomas L|
|Journal||Journal of undergraduate chemistry research|
|Date Published||2009 Summer|
The temperature dependence of the binding constants for human serum albumin and sulfonated metal-phthalocyanines were estimated by fluorescence spectroscopy. Stern-Volmer's analysis and Chipman's fits provided binding data for van't Hoff calculations of the thermodynamic parameters governing these interactions. Results show that the formations of the HSA- phthalocyanine complexes are favorable processes by both the ΔH° and ΔS°. However, the formation of HSA-AIPcS4 has a stronger dependence than HSA-ZnPcS 4on ΔS°.
|Alternate Journal||J Undergrad Chem Res|