Transposition of the great arteries, pulmonary atresia, and multiple ventricular septal defects associated with multiple cardiac rhabdomyomas in a case of tuberous sclerosis.

TitleTransposition of the great arteries, pulmonary atresia, and multiple ventricular septal defects associated with multiple cardiac rhabdomyomas in a case of tuberous sclerosis.
Publication TypeJournal Article
Year of Publication2000
AuthorsJiang ZY, Pircova A, Sekarski N, Hack I, Laurini R, Janzer R, Payot M
JournalPediatric cardiology
Volume21
Issue2
Pagination165-9
Date Published2000 Mar-Apr
Abstract

Multiple cardiac rhabdomyomas are frequently associated with tuberous sclerosis. However, very few cardiac malformations have been described with tuberous sclerosis. We report an unusual case of tuberous sclerosis with cerebral and renal lesions associated with dextrotransposition of the great arteries, pulmonary atresia, patent ductus arteriosus, multiple ventricular septal defects, and parachute mitral valve deformity. After reviewing other cases of congenital heart diseases associated with tuberous sclerosis, emphasis is made on the potential influence of multiple rhabdomyomas developing very early during fetal life on final cardiac structures.

DOI10.1159/000343041
Alternate JournalPediatr Cardiol