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Underlying protective mechanism of α1-adrenoceptor activation against irradiation-induced damage in rat submandibular gland.
|Title||Underlying protective mechanism of α1-adrenoceptor activation against irradiation-induced damage in rat submandibular gland.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Xiang B, Li X-X, Zhang F-Y|
|Journal||Archives of oral biology|
|Date Published||2013 Sep|
Damage to salivary gland after radiotherapy for head and neck malignant tumours can lead to irreversible oral complaints, which severely impair quality of life. The protective effect of α1-adrenoceptor activation on the salivary glands after irradiation has previously been demonstrated. However, the exact mechanism remains unclear. In this study, we investigated the underlying cytoprotective mechanism of α1-adrenoceptor activation in rat submandibular glands after irradiation.
|Alternate Journal||Arch. Oral Biol.|