Visualization of shared genomic regions and meiotic recombination in high-density SNP data.

TitleVisualization of shared genomic regions and meiotic recombination in high-density SNP data.
Publication TypeJournal Article
Year of Publication2009
AuthorsRoberson EDO, Pevsner J
JournalPloS one
Volume4
Issue8
Paginatione6711
Date Published2009
Abstract

A fundamental goal of single nucleotide polymorphism (SNP) genotyping is to determine the sharing of alleles between individuals across genomic loci. Such analyses have diverse applications in defining the relatedness of individuals (including unexpected relationships in nominally unrelated individuals, or consanguinity within pedigrees), analyzing meiotic crossovers, and identifying a broad range of chromosomal anomalies such as hemizygous deletions and uniparental disomy, and analyzing population structure.

DOI10.3109/02699050903285531
Alternate JournalPLoS ONE