In vivo imaging of paraCEST agents using frequency labeled exchange transfer MRI.

TitleIn vivo imaging of paraCEST agents using frequency labeled exchange transfer MRI.
Publication TypeJournal Article
Year of Publication2014
AuthorsLin C-Y, Yadav NN, Ratnakar J, Sherry DA, van Zijl PCM
JournalMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
Volume71
Issue1
Pagination286-93
Date Published2014 Jan
Abstract

A main obstacle to in vivo applications of paramagnetic chemical exchange saturation transfer (paraCEST) is interference from endogenous tissue magnetization transfer contrast (MTC). The suitability of excitation-based frequency labeled exchange transfer (FLEX) to separate out such MTC effects in vivo was tested.

DOI10.1039/c3an00931a
Alternate JournalMagn Reson Med