IDDRC Translational Neuroscience Core

Objective

The Translational Neuroscience Core provides investigators with access to expertise in the analysis of preclinical (animal and human) models of developmental disorders and analysis of relevant clinical samples. Another primary goal of the Translational Neuroscience Core is to facilitate the transfer of basic discoveries to clinical trials. To achieve these objectives, the Core faculty includes scientists with expertise in modeling developmental disorders in animals, and experts who can perform assays that can unravel relevant biochemical/metabolic mechanisms that are not available elsewhere within the Hopkins community. Many of the investigators utilizing the Translational Neuroscience Core are interested in visualizing effects on the brain, and therefore the Core provides training and access to histology and preclinical imaging facilities. Another major function is to provide a group of highly specialized assays that target metabolites and molecules of relevance to intellectual and developmental disorders.