HUGO MOSER RESEARCH INSTITUTE OVERVIEW

Kennedy Krieger’s scientists and researchers are leaders in the worldwide effort to prevent and treat disorders of the brain, spinal cord, and musculoskeletal system.  Our investigators continue to break new ground with innovative magnetic resonance imaging technology, investigate critical areas, such as the role of genetics in developmental disorders, and develop new treatment models and therapies. Kennedy Krieger is committed to sharing our knowledge that can be adapted and used by other healthcare organizations to benefit patients across the country and around the world.

Professional Training Overview

Kennedy Krieger dedicates substantial resources to increasing the number of qualified specialists in the fields of neurological and developmental disabilities. We also take seriously our responsibility not only to improve care through research, but to share that knowledge with others. That is why more than 400 individuals come here to train in a wide variety of disciplines each year. The goals of the Institute’s clinical training programs are twofold: 1) to train leaders in the field of neurodevelopmental disabilities and 2) to help ensure that there is a sufficient number of qualified professionals to meet the needs of children with special health care needs and their families. By training future generations of researchers and professionals – from undergraduate students to current staff – we are ensuring that children everywhere can receive the best possible care.

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A National Research Resource Center for Functional Brain Imaging Technology

The only children's hospital designated as a NIH National Research Resource for functional brain imaging, Kennedy Krieger is breaking new ground with innovative fMRI technology.
Understanding Behaviors Through Observational Research

Discovering the environmental and biological basis of behavior is crucial to understanding and improving treatment outcomes for a wide variety of developmental disorders.
Motion Analysis Research and Laboratory

Using 3D modeling and other innovative technologies, our researchers are studying new methods to improve walking patterns in those with brain injuries.
IAN Research: Advancing Research, Empowering Advocates, Interpreting Findings

The Interactive Autism Network (IAN) is the nation's largest online autism research effort. IAN Research collects data from families online and matches them to studies nationwide.

HUGO MOSER RESEARCH INSTITUTE OVERVIEW

Kennedy Krieger’s scientists and researchers are leaders in the worldwide effort to prevent and treat disorders of the brain, spinal cord, and musculoskeletal system.  Our investigators continue to break new ground with innovative magnetic resonance imaging technology, investigate critical areas, such as the role of genetics in developmental disorders, and develop new treatment models and therapies. Kennedy Krieger is committed to sharing our knowledge that can be adapted and used by other healthcare organizations to benefit patients across the country and around the world.

Participate in Research

Over the years, Kennedy Krieger’s scientists and researchers have made crucial medical discoveries that have led to innovative treatments and improved patient care for individuals with disorders of the brain, spinal cord and musculoskeletal system. Learn more about current research studies you can participate in by visiting our recruiting research studies page. Learn more.

Current Research Projects

Neurotrophin Protection of Hypoxic Ischemic Brain Injury
Principal Investigator: Hossain, Mir Ahamed
Perinatal hypoxia-ischemia (HI) is a major cause of life-long neurological disability such as cerebral palsy. There are few treatments available for this devastating disorder. For the next period of...
Functional and Neurovascular Biomarkers for Huntington’s disease using MRI at 7T
Principal Investigator: Hua, Jun
Oxidative stress and metabolic disturbances in the brain are believed to be involved in HD pathogenesis. Functional and neurovascular brain changes may represent altered neuronal physiology and...
Research Training in Rehabilitation for Brain Injury and Neurological Disability
Principal Investigator: Johnston, Michael
This is the first resubmission of an application for renewal of an Institutional National Research Service Award for a successful postdoctoral training program in medical rehabilitation research that...
Cholesterol Homeostasis in Malignant Glioma
Principal Investigator: Kolar, Elizabeth
The Watkins Lab has observed that when U87 human malignant glioma cells are deficient for a particular acyl- CoA synthetase, ACSVL3, the cells had significantly lower cholesterol levels than did wild...
Multisite RCT of Early Intervention for Spoken Communication in Autism
Principal Investigator: Landa, Rebecca
While significant progress has been made toward identifying effective interventions for preschool-age children with autism (National Research Council, 2001), few scientifically rigorous studies have...
Autism: Social and Communication Predictors in Siblings
Principal Investigator: Landa, Rebecca
This is a longitudinal study of Autism Spectrum Disorders (ASD). Six groups will be assessed longitudinally. Group 1: siblings of probands with autism; (Group 2) late talkers having no family history...
MCH Research - Parent-Mediated Vs. Center-Based Intervention for Toddlers with ASD: An RCT
Principal Investigator: Landa, Rebecca
An ever increasing number of toddlers are identified as being at high risk for ASD. This translates into an increasing demand for Part C Early Intervention services. The importance of intervention...
Effects of Self-Generated Experiences on Social Cognitive Development in Young Children with Autism
Principal Investigator: Landa, Rebecca
Sponsored by Autism Speaks -- 7746. This study will test whether a novel treatment for social impairment in young children with autism spectrum disorders (ASD) leads to improvement at behavioral and...
Development of a Social and Communication Intervention for Preschoolers with Autism
Principal Investigator: Landa, Rebecca
RFA topic and goal:  Autism Spectrum Disorders, Development and Innovation Goal Two Purpose:  Develop and document feasibility and promise of a social and communication curriculum, and...
Suppression of Glioblastoma Stem Cells by Kruppel-Like Factor 9
Principal Investigator: Laterra, John
Glioblastoma stem-like cells (or cancer stem cells, CSCs) maintain a capacity for multi-lineage differentiation and efficiently propagate tumor xenografts that accurately recapitulate the complex...
Brain Cancer Stem Cell Reprogramming by C-MET
Principal Investigator: Laterra, John
Glioblastoma (GBM) is an almost universally fatal brain tumor with an average median survival of only ~15 months. New effective therapies are desperately needed. Small subpopulations of malignant...
Accelerating Autism Research
Principal Investigator: Law, Paul
The proposed project will enable the Interactive Autism Network (IAN) to provide recruitment assistance to qualified research projects throughout the U.S. and to provide a large, validated...
Neuroimaging, Behavior, and Biochemical Correlates in Smith-Lemli-Opitz Syndrome (SLOS)
Principal Investigator: Lee, Ryan
SLOS is an autosomal recessive, multiple malformation syndrome of impaired cholesterol biosynthesis resulting in decreased cholesterol and elevated concentrations of abnormal sterols in tissues and...
Interactive Autism Network Project
Principal Investigator: Lipkin, Paul
The Interactive Autism Network (IAN) was established in 2006 to accelerate autism spectrum disorder (ASD) related research by creating a national online registry and longitudinal research...
Monitoring Prodrug Delivery in Suicide Gene Therapy Using CEST MRI
Principal Investigator: Liu, Guanshu
To accelerate the development of nanotechnologies for drug and gene delivery, it is highly desired to construct nanoparticles with imaging capabilities so that the process of delivery and release can...
Development of ADHD in Preschool Children: Neuroimaging and Behavioral Correlates
Principal Investigator: Mahone, E. Mark
Attention-Deficit/Hyperactivity Disorder (ADHD) has become the most commonly diagnosed form of psychopathology in the preschool years. To address this alarming trend, the overall goal of the proposed...
Optic Nerve Head Synucleinopathy in Glaucoma and Function of Gamma-Synuclein
Principal Investigator: Marsh-Armstrong, Nicholas
The broad long-term goal of this application is to uncover the mechanism of retinal ganglion cell (RGC) degeneration in glaucoma so as to be able to design rational therapeutic interventions based on...
Transcellular Degradation of Mitochondria in the Central Nervous System
Principal Investigator: Marsh-Armstrong, Nicholas
We recently made the surprising discovery that mitochondria from retinal ganglion cell axons are passed onto neighboring astrocytes for degradation in the optic nerve head of normal mice. We present...
Relationship of MRI to ASIA Impairment Scale in Chronic Spinal Cord Injury
Principal Investigator: McDonald, John
Development of imaging correlates of the integrity of spinal cord white matter is needed for optimizing design of clinical trials in spinal cord injury and therapies for patients with chronic spinal...
Advanced Restoration Therapies in Spinal Cord Injury 0186 - FY 08 - 09
Principal Investigator: McDonald, John
Evidence suggests that functional electrical stimulation (FES) can improve certain functions in the central nervous system (CNS) following injury or disease. Using FES-based therapies in spinal cord...
Developing New Multicolor Polypeptide MR Contrast Agents for Stem Cell Tracking
Principal Investigator: McMahon, Michael
Development of new contrast materials is important to expand the diagnostic capabilities of MR at the cellular and molecular level. In particular, providing information on cell migration, trafficking...
Multi-Color Exchange Transfer Imaging of Drug Delivery Nanocarriers
Principal Investigator: McMahon, Michael
This project focuses on the design of biodegradable contrast agents, based on peptides and heterocycles, to be used for the labeling of drug delivery vehicles such as liposomes and polymeric...
OIACEST Islet Cell Capsules for Immunoprotection, MR Detection, and pH Sending
Principal Investigator: McMahon, Michael
Good glycemic control is critical in reducing the end-stage complications of Type I Diabetes Mellitus (TIDM) and, for this reason, islet transplantation (ITx) has received considerable attention in...
Anomalus Motor Physiology in ADHD
Principal Investigator: Mostofsky, Stewart
The hypothesis of this study is that the neuromotor anomalies present in children with ADHD will be associated with deficient intracortical and interhemispheric inhibition of the motor cortex. This...
Neurology of Deficient Response Control in ADHD
Principal Investigator: Mostofsky, Stewart
Building on evidence established in the initial grant period, the overall goals of the proposed study, “Neurology of Deficient Response Control in ADHD,” are to apply advanced neuroimaging and...
Pilot Studies for Event-Related Potential Experiments
Principal Investigator: Ewen, Joshua
This protocol is designed to allow for the recruitment of healthy adult volunteers in order to pilot new paradigms for event-related potential (ERP) research. Since a significant portion of the...
Electrophysiological Studies of Autism
Principal Investigator: Ewen, Joshua
Abnormalities of cortical connectivity have long been suspected to be responsible, at least in part, for the autism phenotype. Research to date has used a number of modalities, but none has the time...
Studies of the Link between Autism and Epilepsy
Principal Investigator: Ewen, Joshua
This research consists of a retrospective record review to examine the link between autism, epilepsy and other clinical symptoms (including, but not limited to, intellectual disability, motor...
Neuropathological Assessment of Neonatal White Matter Injury in Human Autopsy Samples
Principal Investigator: Fatemi, S. Ali
Our group is interested in the study of perinatal white matter injury which affects thousands of prematurely born children every year and is the leading cause of cerebral palsy in this population. We...
Masqueraders of Cerebral Palsy
Principal Investigator: Fatemi, S. Ali
Genetic conditions that manifest movement and postural impairment at perinatal or early childhood periods are often diagnosed with cerebral palsy. Identifying masqueraders of cerebral palsy...
12708A: An open-label study evaluating the Pharmacokinetics and Tolerability of Lu AA21004 in connection with multiple oral dosing of Lu AA21004 in child and adolescent patients with a DSM-IV-TR(TM) diagnosis of Depressive or Anxiety Disorder
Principal Investigator: Findling, Robert
This open-label study will evaluate the pharmacokinetic, tolerability and safety profiles of Lu AA21004 in connection with a multiple oral dosing in child and adolescent patients with a DSM-IV-TR...
SPD489-405: A Phase 4, Randomized, Double-Blind, Multicenter, Parallel Group, Active-Controlled, Dose-Optimization Safety and Efficacy Study of SPD489 (VYVANSE) Compared with OROS-MPH (CONCERTA) with a Placebo Reference Arm, in Adolescents Aged 13-17 Year
Principal Investigator: Findling, Robert
This study aims to evaluate the efficacy, safety, and tolerability of VYVANSE compared with CONCERTA in adolescents (13-17 years of age, inclusive) with ADHD. The study will have 3 phases 1)...
CIL0522D2402: A Multicenter, Open-Label, Sequential-Cohort, Dose-Escalation, 14-Day Study to Explore the Tolerability and Pharmacokinetics of Iloperidone (Fanapt®) 12 to 24 mg/day Followed by 26 Weeks of Flexible Dosing (6 to 24 mg/day) in Adolescent Pati
Principal Investigator: Findling, Robert
This study aims to obtain tolerability, Pharmacokinetic, safety, and efficacy data in adolescent patients (aged 12 to 17 years) requiring treatment with an antipsychotic agent. The study has 2 parts...
A0501093: SPRITES: SERTRALINE PEDIATRIC REGISTRY FOR THE EVALUATION OF SAFETY: A Non-Interventional, Longitudinal, Cohort Study to Evaluate the Effects of Long-Term Sertraline Treatment in Children and Adolescents
Principal Investigator: Findling, Robert
The primary objectives are to evaluate the long-term impact of treatment with sertraline on aspects of cognition, emotional and physical development, and pubertal maturation. Secondary objectives...
A Multi-Center, Randomized, Double-Blind, 12-Week, Parallel Group, Placebo-Controlled Proof of Concept Study to Investigate the Efficacy and Safety of RO5285119 in Individuals with Autism Spectrum Disorders (ASD)
Principal Investigator: Findling, Robert
The main objective of this study is to evaluate the efficacy of 12-week treatment with RO5258119 compared with placebo in treating social communication deficits in adult individuals with ASD as...
VLZ-MD-21: A Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Vilazodone in Adolescent Patients with Major Depressive Disorder
Principal Investigator: Findling, Robert
Purpose This is a double-blind, randomized, placebo-controlled, fixed-dose trial designed to evaluate the efficacy, safety, and tolerability of vilazodone for the treatment of major depressive...
A Randomized, Placebo-Controlled Study to Investigate the Efficacy and Safety of Circadin® to Alleviate Sleep Disturbances in Children with Neurodevelopmental Disabilities
Principal Investigator: Findling, Robert
The purpose of this study is to establish the efficacy and safety of Circadin in children with neurodevelopmental disorders and to determine the dose, this randomized, placebo-controlled study is...
D1050302: A 104-week, flexible-dose, open-label, multicenter, extension study to evaluate the long-term safety and effectiveness of Lurasidone in pediatric subjects with schizophrenia and subjects with irritability associated with autistic disorder
Principal Investigator: Findling, Robert
This open-label extension study is designed to evaluate the safety, tolerability, and effectiveness of lurasidone for the treatment irritability in individuals with autistic disorder. As an extension...
D1050325: A 6-week randomized, parallel, double-blind, placebo-controlled, fixed-dose, multicenter study to evaluate the efficacy and safety of Lurasidone in children and adolescent subjects with irritability associated with autistic disorder
Principal Investigator: Findling, Robert
This is a randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of 2 fixed doses of lurasidone (20 mg/day and 60 mg/day) for 6 weeks compared with placebo in...
A Phase 3, multicenter, three-week, randomized, double-blind, placebo-controlled, parallel-group efficacy and safety trial of flexible doses of oral Ziprasidone in children and adolescents with Bipolar I disorder (current or most recent episode manic)
Principal Investigator: Findling, Robert
This will be a Phase 3, multicenter, 3-week, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy, safety, and tolerability of flexibly dosed ziprasidone...
Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices
Principal Investigator: Findling, Robert
This study will test the ability of a new computer-based tool to screen for attention deficits using a new gaming platform. Children and adolescents, diagnosed with ADHD, will participate in this...
A Multi-Country Analysis of Patients with Chronic Myeloid Leukemia
Principal Investigator: Gary, Devin
This application is based on a study that was originally carried out and completed at George Washington University. All of the data for this study has been collected. No new data will be collected at...
Studies of Hormone Action in Patients with Altered G-protein-coupled Signal Transduction
Principal Investigator: Germain-Lee, Emily
Includes Substudies Entitled: "Study of Growth Hormone Secretion in Patients with Pseudohypoparathyroidism Type 1a (R01 FD002568)" and "Phase 2 Growth Hormone for Treatment of Albright Hereditary...
Rapalogues for Autism Phenotype in TSC: A Feasibility Study
Principal Investigator: Gipson, Tanjala
Tuberous sclerosis complex (TSC) is associated with autism and seizures. Recent studies in animals using rapamycin have shown cognitive improvement. Human studies have demonstrated a reduction in...
CRAD001M2304: A three-arm, randomized, double-blind, placebo-controlled study of the efficacy and safety of two trough-ranges of everolimus as adjunctive therapy in patients with tuberous sclerosis complex (TSC) who have refractory partial-onset seizures
Principal Investigator: Gipson, Tanjala
This study will investigate the efficacy and safety of everolimus, as adjunctive treatment, in patients ages 2-65 years with Tuberous Sclerosis Complex (TSC) that have refractory partial-onset...
Topical Rapamycin to Erase Angiofibromas in TSC - Multicenter Evaluation of Novel Therapy (The TREATMENT Trial)
Principal Investigator: Gipson, Tanjala
The study is a multi-center prospective, randomized, double-blind, placebo-controlled evaluation of the safety and efficacy of a topically applied formulation of rapamycin to cutaneous angiofibromas...
Reward System in Autism
Principal Investigator: Goldberg, Melissa
It is a core feature of autism that social interactions appear to be far less rewarding for autistic children compared to typically developing children. Based on this observation, one would predict...
The effects of treatment preference and treatment integrity on treatment effectiveness
Principal Investigator: Gonzalez, Melissa
The purpose of this research is to determine if allowing a patient or a caregiver choice between different available treatments will affect the treatment effectiveness. Moreover, data on treatment...
Program evaluation of caregivers' behavioral workshop
Principal Investigator: Gonzalez, Melissa
The Pediatric Feeding Disorders Program at Kennedy Krieger Institute provides services aimed at establishing appropriate feeding responses for children who present with a variety of feeding...
Evaluation of Assessment and Treatment Data in Individuals with Intellectual/Developmental Disabilities
Principal Investigator: Hagopian, Louis
The purpose of this retrospective record review is to develop a database to evaluate the efficacy and efficiency of behavior analytic procedures in assessing and treating severe problem behavior.
Establishing Attention as a Reinforcer for Individuals With Autism Spectrum Disorder
Principal Investigator: Hagopian, Louis
Previous research has shown that some individuals with autism spectrum disorder have an atypical reaction to social attention (e.g., praise) delivered by others. In some cases these individuals do...
Delineating subtypes of self-injurious behavior maintained by automatic reinforcement
Principal Investigator: Hagopian, Louis
Self-injurious behavior (SIB) is one of the most serious problems experienced by individuals with intellectual disabilities. The standard of care for the assessment of SIB involves conducting a "...
Pediatric Psychology Consultation-Liaison Services: A Review of Clinical Practice and Patterns
Principal Investigator: Hendricks, Melissa
Pediatric psychology consultation-liaison (CL) service is the most active form of collaboration between pediatric psychologists and health care specialists. The proposed study is a combination of...
Interrelationships among quantitative measures of white matter injury, sensorimotor function and learning profiles in children with cerebral palsy
Principal Investigator: Hoon, Alexander
Injury to white matter pathways is strongly associated with the severity of spastic diplegia in children born preterm. In previous research, we have shown that there is preferential injury in sensory...
Quantitative mapping of the basal ganglia and related structures in children with dyskinetic cerebral palsy
Principal Investigator: Hoon, Alexander
Cerebral palsy (CP) refers to a group of motor-impairment syndromes secondary to genetic and acquired disorders of early brain development.  When the underlying disorder affects the basal...
Comparison of Executive and Adaptive Skills in Individuals Diagnosed with Brain Tumor versus ADHD
Principal Investigator: Jacobson, Lisa
Neuropsychological assessment and screening is a useful means of identifying cognitive deficits in children and adolescents. Expansion of availability of instruments has now permitted an examination...
Kennedy Krieger Institute Family Center - Treatment Effectiveness Study (KKFC-TES)
Principal Investigator: Jamora, Mariflor
The goal of this study is to determine the effectiveness of the various programs within the Kennedy Krieger Family Center (KKFC) using data from a computerized clinical database. Established in 1985...
Psychotropic Medication Use at The Family Center: A 4-Year Analysis
Principal Investigator: Jamora, Mariflor
There have been recent concerns about excessive and inappropriate use of psychotropic medication in foster children, sparked by the recent GAO (Government Accountability Office) report in 2011....
A Randomized, Parallel Group, Double-Blind, Placebo-Controlled, Safety and Exploratory Efficacy and Pharmacokinetic, Study of RO4917523 In Pediatric Patients With Fragile X Syndrome: NP28571
Principal Investigator: Johnston, Michael
The purpose of this study is to evaluate the tolerability and safety of two doses of RO4917523 over 12 weeks in comparison with placebo in pediatric patients with Fragile X Syndrome (FXS), as well as...
Clinical Trials Center Intake, Registry and Questionnaire Database Project
Principal Investigator: Johnston, Michael
The Objectives of this protocol are: a. To create a standard intake process for individuals interested in possible participation in clinical trials at the Clinical Trials Unit (CTU), as well as to...
Rapamycin for Autism Phenotype & seizures in Tuberous Sclerosis (RAPS)
Principal Investigator: Johnston, Michael
Tuberous sclerosis complex (TSC) is associated with autism and seizures. Recent studies in animals using rapamycin have shown cognitive improvement. Human studies have demonstrated a reduction in...
Identification of the Determinants of Exercise
Principal Investigator: Kahng, SungWoo
The overall goals of this project are to develop an assessment procedure, based on functional analysis methodology, to determine what maintains exercise during preferred fitness activities in...
Assessment and Treatment of Problem Behavior in Individuals with Intellectual Disabilities
Principal Investigator: Kahng, SungWoo
The purpose of this research is to prospectively evaluate clinical data obtained from assessment and treatment procedures for behavior disorders in individuals with intellectual disabilities on the...
Evaluations of Teacher Training Procedures
Principal Investigator: Kahng, SungWoo
Teachers and staff members responsible for teaching individuals with intellectual disabilities new skills typically receive training from the supervisors within their organization. A variety of staff...
Student-Centered Behavioral Interventions to Reduce Challenging Behavior in the Classroom
Principal Investigator: Kahng, SungWoo
Aggressive behavior in young children is a known risk factor for youth violence (CDC, 2011). New methods for preventing youth violence and juvenile delinquency are needed to address this growing...
X-Linked Dominant Conradi-Hünermann Syndrome: Clinical and Biochemical Phenotype in Affected Males
Principal Investigator: Kratz, Lisa
X-Linked Dominant Conradi-Hünermann Syndrome (CPDX2) is a rare disorder of cholesterol biosynthesis caused by a deficiency of 3beta-hydroxysteroid-8, 7-isomerase (sterol isomerase), an enzyme encoded...
First Trimester Diagnosis of Smith-Lemli-Opitz Syndrome
Principal Investigator: Kratz, Lisa
Is sterol analysis of direct chorionic villus material or amniotic fluid an accurate method for first trimester diagnosis of Smith-Lemli-Opitz syndrome?
Risk factors for persistent self injury
Principal Investigator: Kurtz, Patricia
The purpose of this study is to assess 5 factors believed to be related to the persistence of self-injurious behavior (SIB): parenting practices, child communication, parent depression, parent stress...
An evaluation of choices across social contexts by children with disabilities exposed to bilingual environments: The role of stimulus and language preference
Principal Investigator: Kurtz, Patricia
For children with disabilities who are exposed to bilingual environments, variations in the language in which leisure items (e.g., books, magazines, music) are presented, the language spoken by the...
Assessment and treatment of severe problem behavior in individuals with intellectual/developmental disabilities
Principal Investigator: Kurtz, Patricia
The purpose of the current proposal is to develop a research database comprised of cases treated for severe problem behavior by the Neurobehavioral Inpatient and Outpatient Programs at KKI. The...
Sleep and Cognitive Function after Mild Traumatic Brain Injury in Adolescents
Principal Investigator: Lam, Janet
After mild traumatic brain injury, many adolescents complain of sleep problems and encephalopathy. This study aims to measure both of these complaints in an objective way to quantify how they are...
Parent-Mediated vs. Center Based Intervention for Toddlers with ASD: an RCT
Principal Investigator: Landa, Rebecca
The major focus of the study is to evaluate the relative impact of two different intervention experiences on social and communication development of minority and underserved toddlers with ASD and...
Autism Treatment Network: Program for the Comprehensive Care and Treatment of Autism
Principal Investigator: Landa, Rebecca
The purpose of this study is to improve medical treatment of children and adolescents with autism by establishing standards of clinical care based on clinical practice and evidence from clinical...
Multisite RCT of Early Intervention for Spoken Communication in Autism
Principal Investigator: Landa, Rebecca
While significant progress has been made toward identifying effective interventions for preschool-age children with autism (National Research Council, 2001), few scientifically rigorous studies have...
Autism: Social and Communication Predictors in Siblings
Principal Investigator: Landa, Rebecca
This is a longitudinal study of Autism Spectrum Disorders (ASD). Six groups will be assessed longitudinally. Group 1: siblings of probands with autism; (Group 2) late talkers having no family history...
Autism and the Development of Relational Awareness
Principal Investigator: Landa, Rebecca
Aims of the proposed research are: to test hypotheses about a deficit in understanding the relationship between objects (e.g., stimulus and reward) in autism, and how this relates to rule learning...
Optimizing Social and Communication Outcomes for Young Children with Autism
Principal Investigator: Landa, Rebecca
The overarching goal of the proposed project is to rigorously test an intervention program for caregivers and their toddlers with autism that is developmentally informed, child-centered and focused...
Developmental and Augmented Intervention for Facilitating Expressive Language
Principal Investigator: Landa, Rebecca
Children who do not communicate with spoken words or an augmentative/alternative communication system are an underserved group among those with autism spectrum disorders (ASD). Because caregivers are...
A Comprehensive Approach to Intervention for Toddlers at Risk for ASD
Principal Investigator: Landa, Rebecca
Research questions are: What are early intervention effects on developmental trajectory and autism symptoms in 14- to 22-month-olds with social and communication delays that indicate high risk for...
Classroom-Based Early Intervention for Toddlers With Autism
Principal Investigator: Landa, Rebecca
The proposed project seeks to continue research into the impact of early intervention targeting interpersonal synchrony on the process of social and communication development in toddlers with non-...

Faculty & Research Scientists