Conditions

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Pelizaeus-Merzbacher Disease

Pelizaeus-Merzbacher disease (PMD) is a rare X-linked leukodystrophy, which means that the mutated gene is on the X chromosome, one of the two sex chromosomes.

Psychiatric Disorders

Examples, Subsets and Synonyms for Psychiatric Disorders: Adjustment Disorders Anxiety Disorders Impulse Control Disorder Mood Disorders Obsessive/Compulsive Disorders Oppositional-Defiant Disorder Panic Disorder Post-Traumatic Stress Disorder Phobias Additional Resources: The American Academy of...

Vanishing White Matter Disease

Vanishing white matter disease (VWM) is a rare autosomal recessive leukodystrophy, which means both copies of the affected gene in each cell have mutations.

Acute Disseminated Encephalomyelitis (ADEM)

Acute Disseminated Encephalomyelitis (ADEM) is a neurological immune-mediated disorder. It damages white matter tissue and causes widespread inflammation of the central nervous system (the brain and spinal cord).

Acute Flaccid Myelitis (AFM)

Acute flaccid myelitis (AFM) is a rare, polio-like condition that affects the body’s nervous system, specifically the spinal cord. The exact cause of the illness is not known, though scientists think it is most likely the result of a viral infection.

Adrenoleukodystrophy (ALD)

Adrenoleukodystrophy (ALD) is a rare, genetic disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland.

Alexander Disease

Alexander disease is a rare autosomal dominant leukodystrophy, which means one copy of the altered affected gene in each cell is sufficient to cause the disorder.

Angelman Syndrome

Angelman syndrome (AS) is a rare neurodevelopmental genetic disorder that affects approximately 1 in 15,000 people. Affected individuals typically have recurrent seizures, balance and coordination issues, developmental delay/intellectual disability and sleep disturbance

Ataxia Telangiectasia (AT)

Ataxia telangiectasia (AT) is a rare, progressive, neurodegenerative childhood disease that affects the nervous system and other body systems.