Lisa
Kratz
,
PhD
707 N. Broadway
Baltimore, MD 21205
United States
About
Dr. Lisa Kratz is the director of the Biochemical Genetics Laboratory at Kennedy Krieger Institute and an associate professor in Pediatrics at The Johns Hopkins University School of Medicine.
Education
Dr. Kratz received her Bachelor of Arts degree from Western Maryland College in 1985, and her doctorate in human genetics from the University of Maryland at Baltimore in 1989. She completed a post-doctoral fellowship in biochemical genetics at the University of Colorado Health Sciences Center in 1991, and was the assistant director of the Biochemical Diseases Detection Laboratory at Yale University from 1991 to 1993. Dr. Kratz was certified by the American Board of Medical Genetics and Genomics in biochemical genetics in 1993 and is a member of the Society For Inherited Metabolic Disorders (SIMD) and the Society for the Study of Inborn Errors of Metabolism (SSIEM). She has been with the Kennedy Krieger Institute since 1993.
Research
Dr. Kratz’s interests focus on the diagnosis of certain inborn errors of metabolism and clinical research related to these disorders. One area of interest involves disorders of cholesterol biosynthesis including Smith-Lemli-Opitz syndrome, Desmosterolosis, X-Linked Dominant Conradi Hünermann Syndrome, and SC4MOL deficiency. Other areas of interest include disorders of creatine synthesis and transport, Barth syndrome, and Mevalonate Kinase deficiency.
Related Links
Elsevier Fingerprint Engine Profile for Lisa Kratz
Google Scholar Profile
Research Publications
Wassif CA, Kratz L, Sparks SE, Wheeler C, Bianconi S, Gropman A, Calis KA, Kelley RI, Tierney E, Porter FD (2016). A placebo-controlled trial of simvastatin therapy in Smith-Lemli-Opitz syndrome. Genet Med. , .
Kratz LE, Albert JS (2016). 2-Ethylhexanoic acid, found in common plasticizers, leads to an artificial increase in C8 acylcarnitine levels in two neonates treated with extracorporeal membrane oxygenation (ECMO). Clin Chim Acta. 461, 59-60.
Driver AM, Kratz LE, Kelley RI, Stottmann RW (2016). Altered cholesterol biosynthesis causes precocious neurogenesis in the developing mouse forebrain. Neurobiol Dis. 91, 69-82.
Gabitova L, Restifo D, Gorin A, Manocha K, Handorf E, Yang DH, Cai KQ, Klein-Szanto AJ, Cunningham D, Kratz LE, Herman GE, Golemis EA, Astsaturov I (2015). Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. Cell Rep. 12(11), 1927-38.
Herman GE, Kratz L (2012). Disorders of sterol synthesis: beyond Smith-Lemli-Opitz syndrome. Am J Med Genet C Semin Med Genet. 160C(4), 301-21.