Recruiting children with sickle cell disease under 5 years of age.

Description: Researchers at the Kennedy Krieger Institute and the Johns Hopkins Hospital are looking for volunteers to participate in a research study on neurodevelopment in young children with sickle cell disease.

To participate in the study, your child must:

• Be under 5 years of age
• Have a diagnosis of sickle cell disease
• Be willing to have a neurodevelopmental evaluation.

This study involves 3 study visits involving:

• History and neurological examination
• Neuropsychological testing
• MRI of the brain
• Blood sample completed at one of the visits above

After the 3 visits above, this study may require annual visits until age 5, including neurological exam and blood sample collection. At their final visit at age 5, this study will require neurological examination, neuropsychological testing, MRI of the brain, and blood sample collection.  Participations will receive compensation .